Cognitive Decline in Older Subjects

Cognitive decline in an older physician.

Predicting cognitive decline in healthy older adults.

OBJECTIVE Authors performed a neuropsychological determination of which individuals in a group of community-dwelling, healthy elderly volunteers would develop cognitive decline. METHODS A group of 155 volunteers reporting good memory and thinking participated in a prospective study over 4 years. Authors monitored cognitive functioning and incidence of Mild Cognitive Impairment (MCI)/Alzheimer...

Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness.

BACKGROUND Persistent postoperative cognitive decline is thought to be a public health problem, but its severity may have been overestimated because of limitations in statistical methodology. This study assessed whether long-term cognitive decline occurred after surgery or illness by using an innovative approach and including participants with early Alzheimer disease to overcome some limitation...

Causes of cognitive decline in diabetes Predictors of cognitive decline in older people with diabetes

This is an uncopyedited electronic version of an article accepted for publication in Diabetes Care. The American Diabetes Association, publisher of Diabetes Care, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisher-authenticated version will be available in a future issue of Diabetes Care in p...

Parahippocampal volume deficits in subjects with aging-associated cognitive decline.

OBJECTIVE Neuropathological evidence suggests that the earliest changes in Alzheimer's disease selectively affect the parahippocampal regions of the brain. This study was conducted to determine if otherwise healthy elderly subjects with mild cognitive impairment had structural volume deficits affecting the parahippocampal gyrus. METHOD Magnetic resonance imaging (MRI) was used to compare glob...